Requests for Applications (RFAs) and Program Announcements (PAs) Relevant to Women's Health, FY 2001-2002
N02-CP-21005-50
Defining and Validating Biomarkers of Risk for Cervical Cancer
The purpose of this RFP is to collect and store cervical tissue specimens that will be used for DNA and RNA analyses in women representative of the four natural history categories in cervical neoplasia: normal, HPV-positive, precancer, and cancer. The main focus of the research is to identify and validate biomarkers at different stages of cervical neoplasia that may be predictive of disease.
PA-01-091
Flexible System to Advance Innovative Research for Cancer Drug Discovery by Small Businesses (FLAIR)
This PA provides a flexible system within the Small Business Innovative Research (SBIR) and Small Business Technology Transfer (STTR) programs to accommodate special needs of the complex drug discovery and development process, from basic discovery through proof-of-principle demonstration in clinical trials, allowing for projects to be presented at all stages of the drug discovery and development process.
PA-02-001
Exploratory Grants for Behavioral Research in Cancer Control
The objective of this PA is to conduct creative, novel research in the behavioral aspects of the cancer control continuum from prevention to end-of-life care and to increase scientific knowledge about health behaviors and health care practitioners' behaviors.
PA-02-002
Clinical Cancer Therapy Research
The overall aims of this initiative are twofold: (1) to stimulate development of innovative therapeutic clinical trials with or without laboratory correlations and (2) to support innovative correlative laboratory studies linked to therapeutic clinical trials to foster the development of interactions between basic science laboratories and clinicians performing the clinical trials.
PA-02-005 (NCI, AHRQ)
Economic Studies in Cancer Prevention, Screening, and Care
Through this PA, the National Cancer Institute (NCI) and the Agency for Health Care Research and Quality (AHRQ) will support research to generate new economic knowledge that will promote the optimal design of cancer prevention and control trial studies and interventions, to facilitate the formulation of effective health care policy related to cancer prevention and control, and to increase the overall understanding of economic aspects of cancer prevention, screening, and care.
PA-02-043 (NIH)
Social and Cultural Dimensions of Health
NCI joins other NIH offices and institutes to support research to (1) elucidate basic social and cultural constructs and processes used in health research, (2) clarify social and cultural factors in the etiology and consequences of health and illness, (3) link basic research to practice for improving prevention, treatment, health services, and dissemination, and (4) explore ethical issues in social and cultural research.
PA-02-169 (NIA, NCI)
Integrating Aging and Cancer Research
The National Institute on Aging (NIA) and NCI will support studies directed at understanding aging and age-related aspects of cancer in older persons, with research spanning the scientific spectrum of cancer control for early detection, diagnosis, prevention, treatment, prognosis, and survivorship.
PA-03-003
Exploratory Studies in Cancer Detection, Diagnosis, and Prognosis
The major goals of this PA are to promote the initial evaluation of new molecular or cellular characteristics of premalignant cells or tumors to identify new biomarkers; the development of assays that will be useful for cancer detection, diagnosis, and/or prognosis; and the evaluation of assays through translational studies to decide whether potential clinical utility justifies further investment.
PA-03-021
Molecular Targets for Cancer Drug Discovery (SBIR/STTR)
The objective is to support young, start-up biotechnology companies and more established firms to conduct preclinical studies toward developing novel drugs for cancer treatment and prevention, with a focus on new molecular targets and agents that modulate them.
PA-03-024 (NCI, NIAAA, NIDA, NICHD)
Molecular Epidemiology of Cancers Associated with Acquired Immunodeficiency
The purpose of this project is to better understand the molecular epidemiology and role of cofactors in the etiology and pathogenesis of preneoplastic conditions and cancers occurring among persons infected with human immunodeficiency virus (HIV), specifically cancers associated with viruses such as human papillomavirus, Epstein Barr virus, human herpes virus 8/Kaposi sarcoma-associated herpes virus, and hepatitis B and C.
PAR-01-101; PAR-01-102 (NCI; NCI, NIEHS)
Development of Novel Technologies for In Vivo Imaging (Phased Innovation Award and SBIR/STTR)
These initiatives are primarily intended to facilitate the development of novel imaging technologies for early detection, screening, diagnosis, or image-guided treatment of cancer and to facilitate clinical evaluation studies of the development that are specifically limited to proof of concept.
PAR-02-037
Small Grants Program for Behavioral Research in Cancer Control
This program is designed to conduct behavioral research investigations in cancer prevention and control. The following program areas focused on behavior and cancer may be supported: screening and early detection, health promotion research, tobacco control research, applications research, health communications and informatics research, basic biobehavioral research, applied surveillance, survivorship, and health disparities.
PAR-02-042 (NCI, AHRQ)
Colorectal Cancer Screening in Primary Care Practice
NCI and AHRQ will promote research to develop the capability for gathering patient, provider, practice, and clinical data and/or conducting interventions to assess and enhance colorectal cancer screening delivery, utilization, and outcomes.
PAR-02-126
Specialized Programs of Research Excellence (SPOREs) in Human Cancer for the Year 2003
NCI supports SPOREs in organ-specific cancers. Applicant institutions must be able to conduct the highest-quality, balanced, translational research on the prevention, etiology, screening, diagnosis, and treatment of a specific organ-site cancer. Current SPOREs are funded in Brain, Breast, Gastrointestinal, Genitourinary, Gynecologic, Head and Neck, Lung, Lymphoma, Ovarian, Prostate, and Skin Cancers.
PAR-03-005
Quick Trials for Novel Cancer Therapies
The focus of this PA is on rapidly ushering translational research through pilot, Phase 1, and Phase 2 clinical trials to ensure timely exploitation of cancer therapeutic approaches, including the development of new cancer prevention agents.
RFA-AT-01-002 (NCCAM, NCI, NIAID, NIMH, NINR)
Complementary and Alternative Medicine (CAM) at the End of Life for Cancer and/or HIV/AIDS
NCI joins the National Center for Complementary and Alternative Medicine in inviting applications to generate scientific knowledge on CAM therapies that alone or in combination with conventional treatment modalities have the potential to improve the quality of life for persons with cancer or HIV/AIDS who are at the end of life.
RFA-CA-01-013
Cancer Care Outcomes Research and Surveillance Consortium (CanCORS)
This RFA, focused on lung and colorectal cancer, will support the development of a system for obtaining details about cancer care beyond the initial diagnosis and limited treatment data that are now routinely collected in high- quality population-based cancer registries. This research will help build the information base needed for measuring and improving the quality of cancer care in the United States, including an examination of disparities in cancer care and outcomes and identifying ways to lessen those disparities.
RFA-CA-02-001
Tissue and Biological Fluids Banks of HIV-Related Malignancies
NCI invites applications from consortia of institutions for cooperative agreements to bank tissue and biological fluids and to maintain associated clinical data from patients with HIV-associated malignancies to be utilized for research, by the research community at large, on the pathogenesis of HIV-associated malignancies and development of more effective therapies.
RFA-CA-03-005
Chemoprevention of Estrogen Receptor (ER)-Negative Breast Cancer Preclinical Studies
The purpose of this initiative is to support the preclinical development and evaluation of chemopreventive strategies that could be rapidly translated to clinical studies and are applicable to women at high risk for development of ER- negative breast cancer.
RFA-CA-03-010
Comprehensive Minority Institution/Cancer Center Partnership
The purpose of this project is to increase the cancer research capabilities at the minority-serving institutions; to increase the number of minority scientists engaged in cancer research and other related cancer activities; and to improve the effectiveness of NCI-designated cancer centers in developing and sustaining activities focused on the disproportionate incidence, mortality, and morbidity in minority populations in the region the cancer center serves.
RFA-CA-03-012
Minority-Based Community Clinical Oncology Program
The Community Oncology and Prevention Trials Research Group (COPTRG), Division of Cancer Prevention, will support domestic institutions with the capability and intent to serve new cancer patients largely from minority populations through cooperative agreements to support cancer clinical trials, to expand the cancer prevention and control research effort using the minority-based Community Clinical Oncology Program (CCOP) network, and to evaluate minority-based CCOP performance and its impact in the community.
RFA-CA-03-015
In Vivo Cellular and Molecular Imaging Centers (ICMICs)
This initiative is designed to capitalize on the extraordinary opportunity for studying cancer noninvasively and, in many cases, quantitatively due to recent advances in molecular imaging modalities, as well as molecular and cellular biology, with an emphasis on multidisciplinary approaches to discover and develop new projects.
RFA-CA-03-016; RFA-CA-03-016 (NIH, ODS)
Diet, DNA Methylation and Other Epigenetic Events, and Cancer Prevention
Diet, DNA Methylation and Other Epigenetic Events, and Cancer Prevention: Competing Supplements
NCI and the Office of Dietary Supplements (ODS), NIH, will support new and existing projects to encourage collaborative research leading to the elucidation of mechanism(s) by which dietary factors influence epigenetic processes, as well as increasing the understanding of these processes in cancer prevention and tumor incidence and behavior.
RFA-CA-03-018
Cooperative Planning Grant for Cancer Disparities Research Partnership Program
Grants funded by this RFA will support the planning, development, and conduct of radiation oncology clinical research trials in institutions that care for a disproportionate number of medically underserved, low-income, ethnic, and minority populations but have not been traditionally involved in NCI-sponsored research. These grants will similarly support nurturing partnerships between applicant institutions and committed and experienced institutions actively involved in NCI-sponsored cancer research.
RFA-OH-01-001 (NIOSH, NCER, NIEHS, NCI)
Endocrine Disruptors: Epidemiologic Approaches
This interagency program by NIOSH, Environmental Protection Agency, NIEHS, and NCI will support research on the relationship between exposure to endocrine disruptors and adverse health effects in humans, particularly reproductive and developmental, with a focus on epidemiologic approaches.
